14. juli 2016

Ray Peat food suggestions

Ray Peat:

Protein deficiency itself contributes to the harm done by toxins, since the liver’s ability to detoxify them depends on adequate nutrition, especially good protein. During stress or fasting, the loss of tissue protein can be minimized by supplementing the minerals, potassium, sodium, magnesium, and calcium. Salt restriction can cause aldosterone to increase, and excess aldosterone causes potassium loss, and increases the use of protein to form ammonia (Norby, et al., 1976; Snart and Taylor, 1978; Welbourne and Francoeur, 1977). Aldosterone secretion increases during the night, and its rise is greater in depressed and stressed people. It inhibits energy metabolism, increases insulin resistance, and increases the formation of proinflammatory substances in fat cells (Kraus, et al., 2005). During aging, salt restriction can produce an exaggerated nocturnal rise in aldosterone. One of the things that happen when there isn't enough sodium in the diet is that more aldosterone is synthesized. Aldosterone causes less sodium to be lost in the urine and sweat, but it achieves that at the expense of the increased loss of potassium, magnesium, and probably calcium. The loss of potassium leads to vasoconstriction, which contributes to heart and kidney failure and high blood pressure. The loss of magnesium contributes to vasoconstriction, inflammation, and bone loss. Magnesium deficiency is extremely common, but a little extra salt in the diet makes it easier to retain the magnesium in our foods. .https://raypeatforum.com/community/attachments/ray_peat_website_articles-pdf.76/

Ray Peat eating suggestions:https://raypeatforum.com/community/threads/ray-peat-diet-food-choices-and-general-guidelines.20/

 Vegetarians often notice temporary exhilaration when they stop eating meat, probably because their thyroid has been suppressed. But a more serious hypothyroid state often follows, from a low protein inadequate vegetarian diet. Low protein diets definitely interfere with the liver’s ability to detoxify estrogen and other stressors.”

A few years ago, most of the nutritional problems that I saw were caused by physicians, by refined convenience foods, and by poverty. Recently, most of the problems seem to be caused by badly designed vegetarian diets, or by acceptance of the idea that 40 grams of protein per day is sufficient. The liver and other organs deteriorate rapidly on low-protein diets. 

"A simple protein deficiency has many surprising effects. It lowers body temperature, and suppresses the thyroid, but it increases inflammation and the tendency of blood to clot. Since the brain and heart and lungs require a continuous supply of essential amino acids if they are to continue functioning, in the absence of dietary protein, cortisol must be produced continuously to mobilize amino acids from the expendable tissues, which are mainly the skeletal muscles."

"When the metabolic rate is optimal, most adults who aren't completely sedentary probably should have around 130 to 150 grams. If their calorie consumption is around 3000 kcal per day, that's about 25% of the calories as protein. Great Lakes Gelatin (cooked collagen), a prothyroid protein is recommended to balance the anti-thyroid amino acids in muscle meats."

"This would emphasize high protein, low unsaturated fats, low iron, and high antioxidant consumption, with a moderate or low starch consumption. In practice, this means that a major part of the diet should be milk, cheese, eggs, shellfish, fruits and coconut oil, with vitamin E and salt as the safest supplements."

Ray: "Yes, people in New Guinea who eat nothing but potatoes for 51 weeks of the year (and pork the other week) have been studied and found to be healthy with no signs of protein deficiency."
~Ray Peat

Proteins:
Daily protein should be at least 80 grams, preferably 100 if you are working or otherwise active. An egg has about 6 grams, a quart of milk about 32 grams, meat, cheese, and fish are usually about 20% protein, so a pound would be enough for a day. It's important to have fruit or other carbohydrate with the protein for efficient metabolism. Milk, cheese, eggs, shellfish are good protein sources, and potato protein is high in quality, if the potato is very well cooked and eaten with butter or cream. Although potatoes contain only about 2% protein, a kilogram of potato has roughly the protein value of a liter of milk (which is 3% protein), because of its high quality. Unless you are buying eggs from a verified grass-fed, free range source he recommends limiting them to one or two a day, and making sure to have plenty of carbohydrate around the same time to prevent sugar crash.

Meats like ground beef, steak, liver, and pork chops are rich in cysteine, which “turns off” the thyroid gland as soon as your body uses up it’s glycogen and ideally shouldn't be your main source of protein. Muscle meats should be eaten with the gelatin it comes with, or supplemental gelatin (see below), to balance out an anti-thyroid amino acid called tryptophan (which is also found in whey protein formulations). Traditionally, muscle meats are eaten with the fat, skin and the gelatin that they come with, so this is mostly an issue in first-world countries where we have protein powders and pure muscle meats readily available. Chicken liver contains such a small amount of fat it's okay to have in addition to or instead of beef liver (which should be consumed weekly). Pork or chicken every 7- 10 days is okay if your metabolic rate (thyroid function) is good. When chicken is stewed, gelatin from the skin is valuable, and much of the fat can be skimmed off(just remember chicken is not optimal). With any of the muscle meats, including fish, gelatin is helpful for balancing the high cysteine, methionine, and tryptophan content. Regarding bacon, Peat says, “The nitrate isn't likely to be a problem if you eat it with orange juice. I fry the bacon to remove some of the fat, and then refry it in coconut oil, to remove most of the PUFA.”

Fatty fish like salmon and herring should be avoided because their fat content is mostly unsaturated; as a general rule, cold blooded animals like fish tend to produce unsaturated fats while warm blooded animals like cows and pigs tend to produce saturated and monounsaturated fats. Cod and sole are good fish, since they have the marine minerals (especially selenium), but low fat content. Tuna is good as protein, but the fat it contains is highly polyunsaturated; eating once a week, especially with homemade coconut mayo should be safe.of course

Regarding his recommendation of daily gelatin:
For an adult, gelatin can be a major protein in the diet, since the need for cysteine and tryptophan decreases greatly when growth slows. Ox-tail soup (boiled for 4 or 5 hours) and lamb shanks have a good proportion of gelatin. I think most stores have gelatin in one pound packages or bigger, for example Great Lakes gelatin is usually around $11 per pound. If a person eats a large serving of meat, it's probably helpful to have 5–10 grams of gelatin at approximately the same time, so that the amino acids enter the blood stream in balance. Asian grocery stores are likely to sell some of the traditional gelatin-rich foods, such as prepared pig skin and ears and tails, and chicken feet. Although the prepared powdered gelatin doesn't require any cooking, dissolving it in hot water makes it digest a little more quickly. It can be incorporated into custards, mousses, ice cream, soups, sauces, cheese cake, pies, etc., or mixed with fruit juices to make desserts or (with juice concentrate) candies.

Peat is a big fan of dairy. He prefers milk with no added vitamins, raw if you can get it, but uses standard pasteurized-homogenized when there’s no alternative. He prefers cheese made without enzymes, just animal rennet. He doesn't use yogurt because of the lactic acid and/or lactobacillus. He avoids anything with gums in it, like cream cheese. Ice cream like Haagen Dazs is okay since it has no carageenan or gums like guar/carob bean– these are often found in foods like cream cheese, canned coconut milk, and half-and-half; make sure that the ice cream does not have any vegetable oil in it as some varieties include this. Regarding yogurt, in quantities of an ounce or so, for flavoring, it's o.k., but the lactic acid content isn't good if you are using yogurt as a major source of your protein and calcium; it triggers the inflammatory reactions, leading to fibrosis eventually, and the immediate effect is to draw down the liver's glycogen stores for energy to convert it into glucose. Cottage cheese, that is, milk curds with salt, is very good, if you can find it without additives, but traditional cottage cheese was almost fat-free, so when they make it with whole milk you should watch for other innovations that might not be beneficial.

Although Peat basically scorns legumes, he said hummus in small amounts isn't nutritionally harmful, though chickpeas and tahini are both allergenic for some people.


“Whey, which is sold as a protein supplement, and egg whites contain too much tryptophan and can be antithyroid if used excessively.” -Ray Peat, PhD
Cheese (milk with the whey removed) contains less tryptophan. Some people have been encouraged to eat only the whites of eggs, “to avoid cholesterol,” but the egg albumin is rich in tryptophan. 
The expensive tender cuts of meat contain excessive amounts of cysteine and tryptophan, but bone broth (gelatin) and the tougher cuts of meat contain more gelatin, which lacks those amino acids.

“For example, whey protein contains much more tryptophan than whole milk or cheese does, and would tend to suppress the thyroid and activate the whole serotonin-stress system. Whey might be good for fattening pigs, but its acceptance in the health food industry as a powdered protein supplement is just another example of the harmful effects of serotonin mythology.” -Ray Peat

Fats:
Best sources are coconut oil and butter; olive oil and macadamia nut oil sparingly. He is a big fan of (refined) coconut oil to stimulate the metabolism. Among nuts and nut oils, macadamia is probably the safest. See the Omega-6 list below for more info.

Carbohydrates:
Have some with every meal to prevent hypoglycemia after eating the proteins.
Fruit and fruit juices – If you're able to do it, try to consume fresh fruits and fruit juices every day. Orange juice is great because of it’s potassium and magnesium content. Tropical fruits and juices are excellent too. If you don’t have a juicer at home, you can buy pasteurized juices with no additives that say “not from concentrate” on the label. Juices that are from concentrate are made up of mostly added water that is flouridated. Fruits in general are fine (tropical are best), but grapefruit is full of phytoestrogens, so avoid it, and berries are full of small seeds you can't avoid, so it's better to skip them. He recommends avoiding bananas and other starchy-poorly-ripened-industrialized fruits, which includes most apples and pears (when these are ripe, peeled and cooked they are much more nutritious, and safer). Organic dried fruits are fine as long as they are not treated with sulfur dioxide; canned fruits are okay, especially if they are in glass. You can have a small apple and some cheese as a snack occasionally if it doesn't cause any digestive or allergic symptoms—the fat in the cheese is protective against the starch in incompletely ripened fruit.

Tubers – Potato, yams; occasionally well-cooked grains in the order of best to least desirable: masa harina, white rice or oats, brown rice. The phytic acid in the oats block absorption of much of the calcium; cooking the oats much longer than usual might improve its nutritional value. Canned plain pumpkin if eaten with some fat is okay, but carrots are less starchy for similar effects.

He recommends eating a raw carrot daily, particularly a raw carrot salad with coconut oil, for both its bowel-protective and an anti-estrogen effect. Summer squash and bamboo shoots are the best cooked vegetables; well cooked kale and broccoli are okay, too. Carrots are best salad. The fiber in whole vegetables helps protect against the effects of the unsaturated fats they contain (in comparison to fruit), which means that juiced vegetables with none of the protective fiber will act as a thyroid inhibitor because of the concentrated PUFAs. There isn’t anything wrong with using vegetables as a smaller part of your diet, but salads and steamed vegetable dishes shouldn’t be the main part of anyone’s diet. He recommends avoiding avocados as they contain so much unsaturated fat that they can be carcinogenic and hepatotoxic (toxic to the liver).

Beverages:
Coffee supports the metabolism but has to be consumed with some sugar or with meal to prevent stress response due to low blood sugar. Because of the tannins in tea, it's important to use either lemon or milk (or cream). The histamine in red wine is a special problem for hypothyroid people, usually it isn't harmful.

Avoid: 
PUFAs and soy. PUFAs are found in processed foods, nuts and seeds and their butters, vegetable oils, margarine. Also keep in mind that if you have been eating PUFAs in the past, the oil change in your tissues takes up to four years during which your fat stores will be releasing enough PUFAs to cause you some troubles, so it requires some patience and also some skillful means to counteract their effects, like getting some extra vitamin E or a little thyroid to counteract their antithyroid action etc. It all depends on how your metabolism works.

Chocolate is okay as long as there are no additives.

For salty cravings, Peat recommends tortilla chips fried in coconut oil, and chicharrones (pork rinds) with no additive but salt (puffed in hot air). Another snack is popcorn popped on the stove in coconut oil, then salted & buttered; the oil and butter are protective against the starch, but it's harder to digest than tortilla chips or chicharrones.

For salt use Mortons Canning and Pickling salt.

Vinegar is a good antiseptic when it's used with raw carrot, but watch for sulfite when using regularly.

Maple syrup is heated to a fairly high temperature, and this creates some sugar-derived chemicals that can be allergenic and might be toxic.

Regarding whey protein, Peat says, “Powdered foods that contain tryptophan are extremely susceptible to harmful oxidation, and the best things are removed, for example calcium, lactose, and casein, with its anti-stress properties.”


Ray Peats own personal diet...




Ray Peats own personal diet from:
http://health.groups.yahoo.com/group/AV ... ssage/5523

Okay, Bruce, this is a summary from my correspondance with her about
what Ray Peat eats (or ate, if he's changed things) and what he
recommends. This is from 2005.

- dairy, fruit and meat are the core of his diet.

dairy for the protein, calcium, and other nutrients
fruits (or other sugars as 2nd choice) for the KAs and EAAs
gelatin to balance the aminos and to replace the need for eating
animal brains and other organs muscle meat as a supplement for
protein magnesium, etc.

- he gets from 120 to 150 grams of protein per day. Doesn't feel quite
right when he goes as low as 100. A few quarts of milk, several ounces
of cheese, gelatin in some form (broth, chicharrones, gummy bears,
etc.), at least a quart of orange juice (or equivalent other fruit),
and the occasional (rotating) eggs, shellfish, fish, and beef, bison,
or lamb, in one or two of his meals.

- says one must always balance protein with sugar (fruit being the
best) because protein alone lowers blood sugar and you need the sugar
to better metabolize the protein. So when he eats protein, he eats
sugar with it: about 1:1 fruit to meat, and about 2:1 fruit to cheese.

- says best to limit meat due to the tryptophan and antimetabolic
properties, but it can be handled if consumed with fruit and gelatin.
He does eat meat almost every day, or just beef or lamb broth When
the meat is aged he doesn't like the taste so he doesn't eat much of it.

- he eats meat with gelatin. The gelatin can be either from regular
powder or from broth cooked no more than 3 hours (otherwise you
degrade the nutrients he says).

- he avoids all fatty fish.

- says chicken should be eaten no more than one meal every 10 days due
to toxins and PUFAs.

- eggs where the chickens are fed corn and soy should be minimally
consumed (for him 2 per week if that), and with one egg you need about
10 ounces of OJ to balance it (because egg protein is a powerful
insulin activator).

- he eats shellfish about once every ten days. Shrimp, scallops,
lobsters have a high ratio of protein to unsaturated fat and help to
insure adequate selenium. Cooks them thoroughly, having known people
who got hepatitis from raw seafood.

- rotates his animal protein sources only because he gets tired of the
same meals, no health reason

- he avoids most vegetables due to their intrinsic (defensive) toxins.
He occasionally makes leaf broth for some extra minerals, but usually
prefers for a cow to process them for him. Mainly he thinks of them as
condiments.

- underground (root/tuber) vegetables are okay if cooked for about 40
minutes, and fruit-vegetables (tomatoes, peppers) are okay if you're
not allergic to them.

- he avoids all other above-ground vegetables, including greens and
many herbs (basil, etc) due to toxins (even if cooked) that far
outweigh the benefits.

- says that cooked young squashes are generally good for everyone, and
although raw shredded carrots are "nutrient subtractive," it's good to
have a plate of them every day because they lower estrogen (and thus
stimulate the thyroid) and accelerate peristalsis.

- he avoids fermented foods. Stopped using black pepper (a fermented
food, apparently) about 30 years ago when he saw the toxicity studies.
Avoids things like apple cider because it is frequently contaminated
with fungal poisons. Says that the more nutritious it is, the more
likely to contain fungal estrogen and other harmful things, unless you
know the actual materials and process used in making it.
Lacto-fermented foods are carcinogenic. Cheese is okay being fermented
because of the strong nutrients in the milk to start with that
vegetables don't have.

- says reason for people's negative reactions to dairy (if the milk
isn't contaminated) is from either preexisting gut damage (from
gluten, for example) or from a low thyroid or protein deficiency
problem. People who are under stress from low thyroid or protein
deficiency have considerable trouble adapting he says, but with
gradual changes (adding dairy back in) the tissues will adjust and do
what they have to do.

- says to eat liver only occasionally because it depresses the thyroid.

- he doesn't eat fruits with seeds that can't be avoided (berries,
figs, etc) because while the antioxidants are good, the benefits are
less than the toxins in the seeds. Other fruits like peaches, plums,
apples, etc should only be eaten if organic and tree-ripened;
otherwise they have very powerful toxins (if unripe or shelf-ripened)
that can cause gut damage. Melons, cherries, and citrus are the best
fruits.

- when off-season, says it's better to eat frozen fruit and juice
rather than rely on importation because many studies show that storage
methods and stress from importation and treatments make them carcinogenic.

- with cheese and milk, the feeding of the animals (grassfed vs.
grainfed) is more the issue than raw vs. pasteurized.

- he avoids all grains. Traditional "proper preparation" methods used
throughout the world to render them less harmful involved using
alkaline mediums such as wood ash (as opposed to "acidic" as Sally
Fallon suggests) and "lime" as in calcium oxide (as opposed to "lime
or lemon juice" as Sally Fallon asserts). Research shows that that
these methods will convert some of the tryptophan to niacin. Using
whey would be especially ineffective as well as problematic due to the
tryptophan.





If a person want to lose weight they should stick with a high fruit, milk, and cheese, and stay away from muscle meats due to lowering metabolism, and also stay away from fish for the same reason. He also said that potatoes and starches will make you fat because they cause an immediate storage of fat due to the high insulin release. He said the reason you want milk/cheese is because of the high calcium content which he says is an excellent metabolism enhancer/booster.

Coconut oil added to the diet can increase the metabolic rate. Small frequent feedings, each combining some carbohydrate and some protein, such as fruit and cheese, often help to keep the metabolic rate higher. Eating raw carrots can prevent the absorption of estrogen from the intestine, allowing the liver to more effectively regulate metabolism. If a person doesn't lose excess weight on a moderately low calorie diet with adequate protein, it's clear that the metabolic rate is low. The number of calories burned is a good indicator of the metabolic rate. The amount of water lost by evaporation is another rough indicator: For each liter of water evaporated, about 1000 calories are burned.

As for sugar vs. starch:
"Starch and glucose efficiently stimulate insulin secretion, and that accelerates the disposition of glucose, activating its conversion to glycogen and fat, as well as its oxidation. Fructose inhibits the stimulation of insulin by glucose, so this means that eating ordinary sugar, sucrose (a disaccharide, consisting of glucose and fructose), in place of starch, will reduce the tendency to store fat."--Peat 
Roots/tubers are second best to fruit. 

Mary Shomon: You've mentioned eggs, milk and gelatin as good for the thyroid. Can you explain a bit more about this?

Dr. Ray Peat: Milk contains a small amount of thyroid and progesterone, but it also contains a good balance of amino acids. For adults, the amino acid balance of cheese might be even better, since the whey portion of milk contains more tryptophan than the curd, and tryptophan excess is significantly antagonistic to thyroid function.

The thyroid gland is extremely quick to adjust its activity, both up and down, except when it's inhibited by stress, or PUFA, or estrogen, etc."-RP

http://raypeat.com/articles/articles/calcium.shtml

A low protein diet, similar to that eaten by a large proportion of women (0.8 g/kg of body weight) increases PTH, and so probably contributes to the development of osteoporosis and the diseases of calcification. In an extreme protein deficiency, there is a shift towards inflammation, serotonin excess, and excessive clotting, which might be related to the effect of the milder, more common protein deficiency.

Most loss of calcium from bones occurs during the night. PTH tends to cycle with prolactin, which increases during the night, along with cortisol and the other stress hormones. These nocturnal hormones probably account for the morning stiffness seen in many rheumatic conditions, connective tissue diseases, and in aging. 
Progesterone, which increases the carbon dioxide content of the tissues, is remarkably able to inhibit the actions of most of the inflammatory and catabolic mediators, and to protect against degenerative calcification and osteoporosis. It also protects against abnormal clotting. PTH increases platelet calcium concentration, and under some conditions can produce inappropriate coagulation. 
Aspirin inhibits the actions of PTH, helping to prevent the calcification of inflamed tissues, and it inhibits the loss of calcium from bones. 
Aspirin helps to increase the oxidation of glucose, reinforcing the effects of thyroid hormone. It can antagonize vitamin K, potentially increasing a bleeding tendency, but with a supplement of K it's safe to test the effects of a standard 5 grain tablet with a meal twice a day, to see if it helps to prevent hyperglycemia.

SM: "I guess what you're saying is 400 calories from orange juice
is not comparative to 400 calories from potatoes or rice."

Ray Peat: "...uh, definitely not. It [the orange juice] stimulates your metabolism and suppresses
the stress hormones."

SM: "Whereas 400 calories from baked potato and rice would increase your stress hormones
and suppress your metabolism?"

RP: "Yeah. And then there's the matter of the starch particles, that if you don't have some saturated fat
with them some of the starch particles can set up a whole pattern of stress and injury by entering
the blood stream."

 when you direct your attention to the sensory surface, rather than to the object, you can notice that the process of noticing affects what you notice. Attention to this process makes it possible to feel the process of thought interacting with sensations. https://raypeatforum.com/community/threads/ray-peat-email-advice-depository.1035/page-8

Yes, any starch can cause endotoxins; long cooking, and butter or cream, can reduce that effect.

 Hypothyroidism is one thing that commonly causes leaky gut, as well as leaky liver, muscles, heart, thyroid gland, etc. The immune system reacts to the leakiness, and although it might be an effect, rather than a cause, the presence of antibodies is sometimes said to show autoimmunity.

The ratio of calcium to phosphate is more important than the absolute amount of calcium. 4 ounces of cheece would usually be enough.

Hypothyroidism is the basic cause of heavy menstruation. Things strong enough to kill an embryo can't be harmless to a person.

 Polyunsaturated fats damage the pancreas and increase stress hormones, while glucose stimulates the renewal of insulin-secreting cells. Fruits provide minerals that help to regulate glucose metaboiism, and help to regulate thyroid function.

 Both sugar and fat stimulate the digestive system hormone that stimulates brain cell renewal. Progesterone helps to reduce tension and excitation, and protects nerves. Pregnenolone reduces stress, and protects nerves.

I don’t think silicon is safe, or has value as a nutrient. I recommend many foods containing considerable amounts of silicon, such as meats, liver, shell fish, bamboo shoots, and mushrooms, but there are many products on the market that contain silicon in forms that can be harmful.

Getting the body temperature too high can deplete glycogen and lower blood glucose, sometimes causing fainting.(About hot tubs).

In response to a question about the theory of body weight having a "set point":






I asked Dr Peat about alopecia areata. Ray Peat said: Hypothyroidism is often a factor, and I think the “autoimmune” process is promoted by endotoxin and nitric oxide from bacterial overgrowth in the small intestine; a pregnenolone supplement can improve response to thyroid supplements. Well cooked mushrooms and bamboo shoots have antiinflammatory, antiseptic effects that can reduce inflammation and might reduce the stress-induced fat deposition. If you don’t get regular sun exposure, vitamin D supplements might help.
"I’ve had a fiber-free diet for many years."
I think periods of intense muscular exertion should be limited to 20 or 30 seconds, followed by rest periods. Otherwise, T3 falls and the stress signals rise. If mental activity has a sense of obligation, of being pushed, it can raise the same stress mediators (serotonin, TSH, prolactin, CRH, cortisol, etc.), but if the attitude is one of opening and exploring new possibilities, it activates restorative processes throughout the body.
Concentric resistance training has an anabolic effect on the whole body. Sprinting is probably o.k. Endurance exercise is the worst. I don't think martial arts are necessarily too stressful. The two things that most often make exercise harmful are activity that keeps the lactic acid high chronically, and "eccentric" exercise, in which muscles are stretched while contracting, as in running downhill.
Thyroid is essential for helping cells to retain magnesium.

Milk, orange juice, and coffee safely accelerate the removal of heavy metals from the tissues.
Vitamins D and K, and calcium are important for stabilizing the heart rhythm.
After the liver's glycogen is depleted, fasting destroys the tissues, starting with the thymus, then the muscles and liver.
The pectin in raw apples causes the intestine to release serotonin into the blood, so well cooked apples have much less effect. Fruits contain almost no salicylic acid.

[Bleeding gums] It's usually a sign of stress, often from over-growth of bacteria in the upper intestine. A daily raw carrot, shredded with a little vinegar and olive oil, can suppress bacteria.

"I occasionally use some powdered gelatin for things like making marshmallows, but usually I get my gelatin from soup, such as ox-tails. lamb shanks, or chicken backs and wings."




"I think pregnenolone can protect against stress and conversion of DHEA to estrogen.

Many of the events involved in inflammation are increased by estrogen, and decreased by vitamin E. Estrogen causes capillaries to become leaky; vitamin E does the opposite. Estrogen increases platelet aggregation, and decreases a factor that inhibits platelet aggregation; vitamin E does the opposite.
Excess clotting is known to be caused by too much estrogen, and also by a vitamin E deficiency.
Clotting leads to fibrosis, and there is clear evidence that vitamin E prevents and cures fibrotic diseases, but this still isn't generally accepted by the powerful medical institutions. Estrogen and polyunsaturated fats increase fibrosis.http://raypeat.com/articles/articles/vitamin-e.shtml

“Besides fasting, or chronic protein deficiency, the common causes of hypothyroidism are excessive stress or ‘aerobic’ (i.e. anaerobic) exercise, and diets containing beans, lentils, nuts, unsaturated fats (including carotene), and undercooked broccoli, cauliflower, cabbage, or mustard greens. Many health conscious people become hypothyroid with a synergistic program of undercooked vegetables, legumes instead of animal proteins, oils instead of butter, carotene instead of vitamin A, and breathless exercise instead of a stimulating life.”  Low protein diets definitely interfere with the liver’s ability to detoxify estrogen and other stressors.” 

Weight Loss

My recommendation is to eat to increase the metabolic rate (usually temperature and heart rate), rather than any particular foods. Usually the increased metabolic rate, with adequate protein, causes some muscle increase, and when that happens the basic calorie requirement will increase. The increase of muscle mass should continue for several weeks, and during that time the weight might increase a little, but usually the loss of water and fat will compensate for the greater muscle mass. I have heard from several people that they think I recommend drinking whole milk, which I don't, because the amount of fat in whole milk is very likely to be fattening when a person is using it to get the needed protein and calcium. When a person wants to lose excess fat, limiting the diet to low fat milk, eggs, orange juice, and a daily carrot or two, will provide the essential nutrients without excess calories.
Per calorie, sugar is less fattening than starch, partly because it stimulates less insulin, and, when it's used with a good diet, because it increases the activity of thyroid hormone. There are several convenient indicators of the metabolic rate--the daily temperature cycle and pulse rate (the temperature should rise after breakfast), the amount of water lost by evaporation, and the speed of relaxation of muscles (Achilles reflex relaxation).
When the polyunsaturated fats in the diet are reduced, the amount of them stored in the tissues decreases for about four years, making it progressively easier to keep the metabolic rate up, and stress hormones down.
The ratio of calcium to phosphate is very important; that's why milk and cheese are so valuable for weight loss, or for preventing weight gain. For people who aren't very active, low fat milk and cheese are better, because the extra fat calories aren't needed.
There are different kinds of weight gain. When a person's metabolic rate increases, and stress hormones decrease, for example when adding two quarts of milk to the daily diet, their muscle mass is likely to increase, even while their fat is decreasing. Since muscle burns fat faster than fat does, caloric requirements will gradually increase.
People on a standard diet will typically burn 200 or 300 more calories per day when that amount of sugar is added to their diet; but if extra fat is added, too, some of the extra calories are likely to be deposited as fat. It's important to watch the signs of changing heat production as the diet changes.
Yes, I know people who have lost weight just by eating a raw carrot every day, reducing endotoxin stress. The liver treats PUFA as it treats toxins, but when their concentration is too high, they poison the detoxifying system. Oleic acid, which we can make ourselves from carbohydrates, greatly activates the detox enzyme system.
Yes, that's why a resistant (antiseptic) fiber such as bamboo shoots or raw carrot helps with weight loss, it reduces endotoxin and the stress hormones, and lets the liver metabolize more effectively.
It's the stored PUFA, released by stress or hunger, that slow metabolism. Niacinamide helps to lower free fatty acids, and good nutrition will allow the liver to slowly detoxify the PUFA, if it isn't being flooded with large amounts of them. A small amount of coconut oil with each meal will increase the ability to oxidize fat, by momentarily stopping the antithyroid effect of the PUFA. Aspirin is another thing that reduces the stress-related increase of free fatty acids, stimulating metabolism. Taking a thyroid supplement is reasonable until the ratio of saturated fats to PUFA is about 2 to 1.
Yes, it's best to lose it slowly. When I tried adding about a tablespoon of coconut oil once a day I lost about two pounds a week, for several weeks, without eating less.
Some muscle-building resistance exercise might help to increase the anabolic ratio, reducing the belly fat.



The adrenal glands use it to produce their antistress hormones, and when there is enough progesterone, they don't have to produce the potentially harmful cortisol. In a progesterone deficiency, we produce too much cortisol, and excessive cortisol causes osteoporosis, aging of the skin, damage to brain cells, and the accumulation of fat, especially on the back and abdomen. 

 If a woman has ovaries, progesterone helps them to regulate themselves and their hormone production. It helps to restore normal functioning of the thyroid and other glands. For migraines, it has been taken orally just as the symptoms begin. An average person produces about 30 milligrams daily during the 2nd two weeks. The solution I have used contains approximately 3 or 4 milligrams of progesterone per small drop. Three to four drops, or about 10 to 15 milligrams of progesterone, is often enough to bring the progesterone level up to normal. That amount can be taken days 14 through 28 of the menstrual cycle; this amount may be repeated once or twice during the day as needed to alleviate symptoms.  

The cyclic use of progesterone, two weeks on, two weeks off, will often keep the normal menstrual cycle going. Low thyroid is one cause of excess estrogen, and when high estrogen is combined with low thyroid, the skin looks relatively bloodless.  Dark cloudy winters in England or the Pacific Northwest are powerful stressors, and cause lower production of progesterone in women, and testosterone in men. Toxins can produce similar symptoms, as can nutritional deficiencies. A very common cause of an estrogen excess is a dietary protein deficiency--the liver simply cannot detoxify estrogen when it is under-nourished. 

Progesterone stimulates the ovaries and adrenals to produce progesterone, and it also activates the thyroid, so one dose can sometimes have prolonged effects. It shouldn't be necessary to keep using progesterone indefinitely, unless the ovaries have been removed. In slender post-menopausal women, 10 mg. per day is usually enough to prevent progesterone deficiency symptoms.

Recent publications are showing that excess phosphate can increase inflammation, tissue atrophy, calcification of blood vessels, cancer, dementia, and, in general, the processes of aging. While fructose lowers intracellular phosphate, it also lowers the amount that the intestine absorbs from food. The "anti-aging" protein, klotho, increases the ability of the kidneys to excrete phosphate , and like fructose, it supports energy production and maintains thermogenesis.  Niacinamide is another nutrient that lowers serum phosphate and also by reducing its reabsorption by the kidneys. The foods naturally highest in phosphate, relative to calcium, are cereals, legumes, meats, and fish. Many prepared foods contain added phosphate. Foods with a higher, safer ratio of calcium to phosphate are leaves, such as kale, turnip greens, and beet greens, and many fruits, milk, and cheese. Coffee, besides being a good source of magnesium, is probably helpful for lowering phosphate, by its antagonism to adenosine.

Long hours of daylight are known to increase progesterone production. Chronic constipation, and anxiety which decreases blood circulation in the intestine, can increase the liver's exposure to endotoxin. Endotoxin (like intense physical activity) causes the estrogen concentration of the blood to rise. Diets that speed intestinal peristalsis might be expected to postpone menopause. A deficiency of thyroid, vitamin A, and LDL-cholesterol can also prevent the synthesis of progesterone. Vitamin E: Estrogen antagonist, energy promoter, and anti-inflammatory. B vitamin deficiencies alone are enough to cause the liver's underactivity, and to cause estrogen dominance, and a simple vitamin A deficiency causes an inability to use protein efficiently or to make progesterone, and in itself mimics some of the effects of estrogen."

People under stress, or who have a thyroid deficiency, or who don't eat enough protein, typically have elevated estrogen levels. The accumulation of the “essential fatty acids,” the polyunsaturated oils, in the tissues promotes the action of estrogen in a variety of ways, and this effect of diet tends to be cumulative, and to be self-accelerating. 

(Me: so to lower estrogen (and the edema before the period) daylight, vitamine e, selenium, coffee, salt, enough protein, vitamine d, b6 and carrots are good. Avoid plastic bottles, PUFA)

There are several prescription drugs that protect against serotonin excess, but thyroid and gelatin (or glycine, as in magnesium glycinate) are protective against the serotonin and melatonin toxicities.

Others on the ray peat forum says:
Taurine is an amino acid, and Ray Peat often warns against taking free amino acids.
Avoiding food that irritate stomach is the most effective way to lower serotonin and using daily raw carrot salad. I read one study that found papaya do the best
job of breaking down gelatin protein. 
Daily human doses of caffeine in the 200mg-400mg range flush the liver of its fat. Also, since caffeine is anti-estrogenic that would help the liver detox even better since it relieves it of estrogen, which Peat said is the single biggest burden for the liver (except PUFA of course).
Eating fructose rich carbohydrate increases phosphorus
loss. If your carbs are mostly from sucrose and fruits then you can get away
with higher amount of phosphorus in the diet. It is a big problem when
starch is the main carb,phosphorus high and calcium is low.
RP mentioned that the ratio of calcium to phosphorus should be at least 1:2.
That is if calcium is 800 mg then phosphorus can not be more than 1600 mg.
But he also mentioned that ideally it should be 1:1, if there is 800 mg calcium then
there should be 800 mg of phosphorus. He also mentioned that
2:1 ratio is safe. Niacinamide is a very powerful tool for lowering phosphorus. 

 Vitamin E lowers prolactin. Lower prolactin means higher dopamine, higher testosterone, and lower serotonin. Now, some of that testosterone may aromatize to estrogen if you are under stress but this is where again Vitamin E and vitamin K come into play. Vitamin K (only menatetrenone a.k.a. MK-4 has been shown to do this) is a true aromatase inhibitor. 

Finally, even if any testosterone does aromatize then vitamin E acts like an estrogen "receptor" antagonist and in doses of 2,500mg lowered estrogen levels by 65%. If you add vitamin A and vitamin D to this duo should help with estrogen even more.

The drug pCPA Ray wrote about does the same thing as niacinamide - lowers serotonin and boosts libido like nothing else.



When estrogen is low, as Ray peat said, you should NOT be retaining any excess water.


Peat suggested in 'Nutrition for Women' that estrogen may increase the tendency for one to have "little" orgasms, with the need to have many in succession. When hormones were more in balance the tendency was to have one large more satisfying orgasm, often followed by sleep.
What are Peat's guidelines for defining hypothyroid? There are plenty of signs/symptoms - cholesterol (high), ceruloplasmin (low), prolactin (high), DHEA-S (low), pregnenolone (low), testosterone (low), CO2 (low), liver enzymes (high), TSH (high), T3 (low), etc. that can give indication of something is not functioning well. Peat said that cholesterol, reflexes, pulse, and temp are the best test for hypothyroidism and was used back in the early 20th century, but even pulse and temp are a good indicator.

Matt Stone says (180 degree eating plan)

http://180degreehealth.com/low-carb-rehab/
The belief that the cells’ exposure to insulin causes them to become resistant over time is the fallacy that low-carb proponents live under. This is absolutely false.

Insulin resistance is caused by a low metabolism. When the metabolism is normal, insulin resistance cannot be induced. Insulin resistance is a natural starvation response. It is deployed to store fat, increase hunger, reduce energy expenditure, and so on.

It appears that refined sugar and perhaps flour and vegetable oils have the unique ability to slow down the metabolism.

A no-sugar high-calorie diet that is not restricted in any way, is probably the best fully natural way to counter a low-metabolism.

Going into ketosis will stimulate your adrenals and cause the heart to beat faster, the eyes to dilate, the body to sleep less, and the brain to be more focused.

When the glycemic index came out, science abandoned good judgment, common sense, and observation and instead jumped on the foolish idea that a snickers bar was better for a diabetic than a potato – despite information that spans galaxies in the other direction on that topic.
What matters is how much insulin is secreted in proportion to the rise in blood sugar. Insulin isn’t just secreted to match the amount of glucose. It goes higher in response to sweet tastes, which is why it comes crashing back down.

It’s no secret that reducing carbohydrates in your diet to an extreme level slows down the metabolism.  It does this by lowering production and/or synthesis of the active thyroid hormone – the one that REALLY counts, T3 – triiodothyronine. Low-carb=less than 50 grams per day.

I'm eating mostly cooked rice and potatoes with plenty of vegetables and greens, animal protein with 1 meal per day or so but not all. Eat to fullness when hungry – whether it's 2 meals per day or 5 depends on the day. About 20% of my diet is fruit, eaten as a monomeal – completely by itself.

There is no doubt in my mind that eating very frequently (every couple of hours) of mostly starch-based meals will be the most effective at actually reversing and overcoming hypoglycemia and adrenal exhaustion. Remember, it is the adrenal hormones that keep healthy people satiated between meals – they rise when postprandial insulin levels fall a couple hours after eating and trigger the release of stored energy. Without that, however, and producing way too much insulin in proportion to glucose ingested as seen in hypoglycemia, you will get hungry shortly thereafter, and traumatize the adrenals in the process. http://180degreehealth.com/low-carb-lowers-metabolism/

For those wanting to increase body temp. but concerned about weight gain, I will state rather emphatically that when fat intake is low enough, fat storage becomes extremely unlikely, even eating above maintenance calories and gaining scale weight.

Feeling drowsy after a meal, having really negative emotions (irrational crying, depression, anger), and other things ( digestive problems and ski break outs) are symptoms of poor glucose tolerance.

From a strictly physiological standpoint, if a person's adrenal glands were really in need of rest to achieve any level of healing, the greater the meal frequency the better. Also, the greater the ratio of starch to fats and proteins. But for healing shot adrenals, I don't think there's any question that the best way to heal them up in the shortest amount of time would be to eat and sleep all day.

Fructose causes the greatest blood sugar instability of any other sugar.

You can lose weight on any calorie controlled approach, and lose mostly fat on any calorie-controlled approach. The benefit of the whole foods approach is that your own hormones can work with you, and have you reduce your calories automatically instead of using a calculator to do it. The advantage is that appetite is reduced while metabolism stays up vs. calorie restriction on processed foods which has the opposite effect. That's the difference. When refined carbs are taken out of someone's diet, caloric intake can drop by up to 40% with no negative impact on metabolism. Clearly there is something fundamentally different about a whole foods vs. refined foods diet.

Paleo diet was just the diet that human beings were forced to eat when moving into Northern climates that they could survive in, but were not designed for.  Keep in mind that 99% of the 3 billion lean people on earth eat a high-starch diet.

Barry Sears emphatically states:
“…the longer you stay in ketosis, the more your fat cells adapt so that they are transformed into ‘fat magnets,’ becoming 10 times more active in accumulating fat…A high-protein, low-carbohydrate diet drives insulin levels too low, thereby causing hypotension, fatigue, irritability, lack of mental clarity, loss of muscle mass, increased hunger, and rapid fat regain when carbohydrates are reintroduced into the diet.

Broda Barnes stated:
“…it has been clearly established that a high protein diet lowers the metabolic rate, [therefore] symptoms of hypothyroidism will be aggravated…"Apparently, a diet high in protein requires additional thyroid for its metabolism.”

As you lose weight, metabolism slows down.  As metabolism slows down, you form fewer and fewer red blood cells (and platelets, and leukocytes, etc.) – the result being “too little blood,” basically what the word “anemia” means. http://180degreehealth.com/thyroid-and-nosebleeds-heavy-periods-bleeding-gums-bruising-anemia-and-low-platelet-countitp/

“Eat plenty of food, don’t overexert yourself physically or mentally, get plenty of sleep, eat only saturated fats and keep omega 6 polyunsaturated fat ingestion to a minimum, get sufficient but not excessive amounts of quality protein, and eat plenty of high-glycemic starch at every meal.”
This generally lowers the activity of the sympathetic nervous system, increases thyroid activity, improves glycogen storage, and starts shuttling glucose from ingested food into muscle cells where it creates muscle growth and the generation of heat and energy.  This reduces insulin resistance. Chronic stress hormone secretion is the primary root cause of insulin resistance. Experiences of high-adrenaline states indicative of crashing glucose levels .http://180degreehealth.com/starch-lowers-insulin/ You get inflammation in your hands and arms and awful BG numbers like us when we ate carbs after being on a low-carb diet for a while. Low-carb dieting makes your body's ability to use glucose properly even worse.

Refined foods are sometimes preferable for someone trying to rehabilitate metabolic rate. "Overfeeding" as I define it ( as eating beyond appetite or eating slightly more than what one would eat if eating ad libitum) is very useful for anyone with a low metabolic rate seeing to overcome that.

You feel better on low-carb because your adrenaline is running higher. And you are staying in a sympathetic dominant state. This is fine but it does age you faster and is anti-thyroid. Change something like your metabolic rate and you will change how you respond to just about everything. The basic premise is that high cortisol/low thyroid is the root cause of the development of insulin resistance.  Coffee is one of the almighty sugar crashers by the way. Spike your blood sugar. That’s how you improve your “glucose metabolism fitness.” It should actually increase your storage depot for carbohydrates, lead to improved glucose clearance, and improve your initial insulin response to food (all go hand in hand).  insulin response to food (all go hand in hand).  Your adrenals are driving the high blood sugar in the morning, which is why it goes up once you start moving around (going from relaxed to active). If I were you I would eat tons of carbs right away, to shut those down and get you back in a parasympathetic-driven state (which should make you feel much more calm and relaxed in the morning). Lunch is the best time to eat more meat, fat, and starch. Whereas breakfast is usually superior if it is mostly sugars and starches. Protein and vegetables at dinner.

My blood glucose does not skyrocket no matter what I eat. At any time. That is achievable when glucose clearance reaches the point of excellence. Also, insulin spiking to high levels after a meal is a marker of excellent health. It’s when the insulin no longer rises after meals that you see high blood sugar that doesn’t clear and return to normal quickly. There isn't any evidence that “spiking” insulin wears out beta cells.

Metabolic issues and obesity almost ALWAYS have the circadian rhythms backwards – waking up feeling tired and not hungry (low cortisol, high serotonin), and going to bed hungry (craving calorie-dense sugary foods, white flour products, and alcohol specifically) and not tired (high cortisol, low serotonin). This can mostly be attributed to, I believe, the delicate balance between serotonin and cortisol – which is impacted most heavily by the carbohydrate to protein ratio of the last meal you ate, as well as calorie intake. Eating starch, WITHOUT accompanying protein (a few bites of a baked potato) before bedtime assists in getting tryptophan across the blood-brain barrier where it is converted to serotonin, then melatonin – helping you fall asleep and have incredible dreams.

Advice for a man who has low metabolism after years on low carb:
My ideas for you would be to cut the exercise down to stretching and walking, lightly – while continuing to eat as much nutritious food as you can get in you until you complete the process. Completing the process involves going full-throttle until weight gain ceases, hunger starts to subside, and muscle starts replacing body fat spontaneously. Be persistent. For now, step one would be to fix the carbohydrate sensitivity that ketosis has given you by eating a diet that is very high in carbohydrates by percentage. That means displacing some fat and protein with carbohydrate calories for up to a few weeks before getting more balanced again.

The key for me is seeing repeatedly that I absolutely will not store more fat than I burn unless there is sugar in my diet (combined with fat, protein, and starch). But then again, remove any one of those elements (except starch) and I lose weight.
I have also repeatedly seen people on SAD lose 10 pounds or more in one month by restricting fructose-containing sugars… this without any conscious effort at all to lose weight, restrict calories, or exercise more.

Richard J. Johnson also acknowledges that fructose increases postprandial ATP generation the most, which he feels has the long-term consequence of exhausting cellular ATP generation and lowering the metabolism despite postprandial increase. I can eat sugar all day long by itself and not gain weight. No one can, because insufficient protein intake triggers catabolic hormones, and you lose weight from lean tissue losses a lot faster than you lose fat weight. As far as reversal while underfeeding, cutting carbs increases fatty acid oxidation, meaning that more fat and less glucose is used for fuel. This spares lean mass when the catecholamines rise. If catecholamines rise (in calorie deficit) and your body is oxidizing mostly glucose for fuel, get ready to lose some lean mass.

As far as reversal while underfeeding, cutting carbs increases fatty acid oxidation, meaning that more fat and less glucose is used for fuel. This spares lean mass when the catecholamines rise. If catecholamines rise (in calorie deficit) and your body is oxidizing mostly glucose for fuel, get ready to lose some lean mass.


My body temperature dropped when I started eating more carbohydrates as well, but so did my pulse rate. My pulse rate was by far the highest on zero carb, and is much lower now when I feel my best (~50 bpm).

At the very least you should consider brief interruptions in fat loss to overfeed on very high-carb/low-fat. This will rebuild any lost muscle through dieting without fat gain as long as fat is under 10% of calories when overfeeding.

Overweight people ARE starving precisely because the food they eat is siphoned off into fat cells instead of used for energy like it is in a healthy person.http://180degreehealth.com/ancel-keys-and-the-biology-of-human-starvation/

REACTIVE HYPOCLYCEMIA http://180degreehealth.com/reactive-hypoglycemia/
 Dr. Barnes on hypoglycemia:
“…it has been clearly established that a high protein diet lowers the metabolic rate, [therefore] symptoms of hypothyroidism will be aggravated… Hypoglycemia may be controlled on the high protein diet, but the other symptoms of thyroid deficiency which usually accompany hypoglycemia are aggravated.”
Consuming EXCESS protein beyond what your body uses (and your body uses very little for muscle-building if you are not eating very many carbohydrates) forces the excess protein to be burned as energy (protein oxidation). Uh oh, you need a rise in adrenal hormones like cortisol to use protein as fuel, which are antagonistic to the thyroid, increase insulin resistance, etc.
“To date, when the symptoms of hypothyroidism are relieved, hypoglycemia, like the others, disappears.”
 My preference for switching to high carbs is just diving in, and probably keeping meal size very small – eating every 2 hours for someone just coming out of the gates.

And yes, the liver has a lot to do with hypoglycemia. Anything containing fructose or alcohol are the only things that have ever given me classic hypoglycemic reactions (wake up at 4am, sweating, with hunger pangs for example). 

Although overfeeding on a mixed diet works really well for increasing body temps, improving digestion, improving sleep, and all the many things people have mentioned – it's also pretty clear that 80% of people gain fat eating to appetite or beyond appetite on a diet like that. If fat intake is low enough while overfeeding, fat gain is impossible and lean mass gains are guaranteed. Your body has to do something with the excess energy intake, and in the absence of fat, you gain nothing but lean mass while overfeeding. This, in and of itself, is a very important discovery.
Also, excess carbohydrate increases thermogenesis, and fat does not stimulate the metabolism the same way that carbohydrate does. Carbohydrate has limited storage capacity, so eating excess carbohydrate increases body heat, physical energy, etc. whereas excess fat is just stored.

Vladimir Heiskanen has made this blog post at 180 degree health:

 According to animal studies, excessive amounts of methionine might predispose to the metabolic syndrome. In some animal studies methionine restriction has been shown to protect against obesity, and to prolong lifespan. However, it seems that the main “benefits” of methionine restriction also require simultaneous cysteine restriction, and many of the beneficial effects are likely to be a consequence of some kind of a deficiency. It has also been suggested that some of the harmful effects of excess methionine might be caused by glycine depletion, because glycine is needed in the clearance of excess methionine. There are numerous studies showing that glycine protects rodents from inflammation, metabolic syndrome, cancer, diabetes, animal protein, endotoxin, hypoxia, hemorrhagic shock, lead and cadmium toxicity, dental caries, intestinal damage and many other thing.  Rice protein has twice as much glycine and a little bit less methionine than casein, and it is possible that this is an important factor causing these beneficial effects. Examples of protein sources with a good glycine:methionine ratio would include: gelatin, scallop, fish, potatoes, lentils and beans.. Casein might decrease the harmful effects of a high-fat diet by decreasing fat absorption in the intestines.
– Some studies have been showing that individuals with insulin resistance might have lower plasma levels of glycine, histidine, and taurine than healthy people. Because this “deficiency” of anti-inflammatory amino acids might lead to more inflammation, it is possible that people with insulin resistance would benefit most from the amino acid supplementation.http://180degreehealth.com/amino-acids-metabolic-syndrome/
http://180degreehealth.com/rrarf-addendum/ :While RRARF (Rehabilitative Rest and Agressive Re-Feeding) is very successful at raising body temperature, improving digestion and overall well-being – one question remains…. Can it be done more efficiently? Can it be improved upon?
By more efficiently, I mean with less fat gain and greater lean body mass gain as well as a greater rise in temperature per calorie ingested.
I believe the answer to those questions is “yes.” So what’s better? Getting more calories from starches or getting more calories from fat?
Upon close scrutiny of the literature on overfeeding, a clear picture emerges. Straight studies comparing overfeeding with a high-fat/low-starch diet vs. a high-starch/low-fat diet yields clear-cut results. The higher the ratio of starch to fat when overfeeding, the greater the lean body mass gains and the lesser the body fat gains. Not only that, but since starch is not something that the body can readily store like it can fat molecules, the excess calories ingested MUST force an increase in body heat and physical energy to a much greater degree than fat overfeeding.
 When large quantities of fructose are ingested during overfeeding, the effect is very fattening because a great deal of the fructose is converted to fat in the liver. However, this is not true when talking about starch overfeeding.Of the starches, those highest in amylose content and resistant starch – such as legumes, red potatoes, corn, and intact whole grains like Basmati rice (vs. those ground into flour as in bread/pasta) – particularly those that have been cooked and then chilled which forms a type of metabolically-stimulating resistant starch known as RS3, are ideal. A version of RRARF where these types of starchy foods are maximized and other foods more or less minimized in comparison is probably the most efficient route to take. 
The reasons why that is goes far beyond a larger increase in lean body mass in comparison to fat gains, but incorporates positive changes in the microbial environment of the gut, intestinal production of the most metabolically-stimulating and insulin-sensitizing fatty acids known (such as butyric and propionic acids), and perhaps most-importantly – pronounced appetite inhibition with an increase in metabolism, meaning that weight gain is minimal or weight is even lost eating to appetite while metabolism simultaneously rises (the Holy Grail of health and weight loss).
For overfeeding, I really don't think much meat/fish/dairy is needed at all. 1 portion per day is more than enough while eating beyond appetite. I'm actually prefering far less. I feel best when I wait until I really crave animal protein to eat it – which usually ends up being once every 3-4 days.
 The higher the starch to fat ratio, the greater the muscle gain to fat gain if weight is gained eating to appetite (for those coming off the SAD, weight loss is more likely).
A typical meal might be 1 pound of roasted potatoes sprinkled with a little cheese, and a plate of rice and beans with lots of salsa.
Fat is very healing for someone coming off a prolonged low-fat, low-calorie restricted diet. But a very large portion of people trying RRARF are former low-carbers, and they stand to get more healing from high-carb intake.
Either way, if you are coming from low-fat/low-calorie damage or low-carb damage and you eat lots of both together to appetite, you'll see a rise in body fat almost guaranteed. Not to say that this isn't healing. It is. It's awesome.
Starch overfeeding doesn't have the same result. Excess starch does not become fat. Excess simple sugar becomes fat, and doesn't improve insulin sensitivity. The opposite actually. But in real life, what happens is that insulin levels go up if people are really overfeeding hard, but in the absence of fat any weight gained is almost pure muscle.
But most spontaneously eat fewer calories, have a drop in insulin, lose fat.

Here are the prime factors in the flavor-calorie theory, which explains numerous diets all under one umbrella…
1.) Calorie density – the more calorie-dense a food is, the more it triggers an activation of reward centers in the brain and a mysterious rise in weight set point.
2.) Absorption rate – the faster a food is absorbed, the stronger the flavor-calorie association and the larger the rise in the activation of reward centers in the brain and a rise in set point that occurs when these pleasure centers are tickled.
3.) Flavor-intensity – the more highly-flavored the food is, the more it raises set point
4.) Food familiarity – the more you eat ditto foods with a strong flavor-calorie association (like, say, Cool Ranch Doritos), the more you start to prefer those foods, the stronger the flavor-calorie association becomes, and the more fattening those foods become.
5.) Liquid vs. Solid – Liquids, in general, promote stronger flavor-calorie associations and are more fattening than solid foods – raising the set point.
7) Feeding humans less calorie-dense foods, such as a diet high in fiber and water content from fruit, vegetables, and unrefined starches causes a massive decrease in calorie consumption – up to an instant 40% decrease with no decrease in satiation reported (from Burkitt et. al.’s Western Disease).
11) Low-carb diets that contain artificial sweeteners often negate the hunger-suppression and weight loss effect of a low-carb diet. Even Atkins reported this, and advised those who weren’t losing weight to make sure they excluded aspartame from their diets.
Fruit, which has a very low-calorie density, eaten by itself, does NOT form strong flavor-calorie associations. When consumed with a high-calorie load after a mixed meal, I find fruit to be very fattening, and juices even more so, which would be expected if Roberts’s theory is accurate.
 Those attempting to lose weight may find much better success…
– eating almost exclusively homecooked whole foods
-cooking differently each time or with the addition of different spice combinations to reduce flavor-calorie associations
-eating lots of food that is not calorie dense – like root vegetables and vegetables
-avoiding all liquid calories
-eating foods that require lots of chewing
-keeping fat intake reasonable (which decreases flavor-calorie associations), and being wary about foods with strong flavor-calorie associations where fat and carbohydrate are conjoined and in ditto form – pizza, ice cream, fast food, chips, cookies, etc.
For more on Seth’s theory, read the Shangri-La Diet or Seth’s free report here:
Fat overfeeding causes the most fat gain and the least thermogenesis.
Essentially, the brain releases dopamine in proportion to calorie density. Now, 7-day averages, not overfeeding, I'm probably at:
100 grams protein
70 grams fat
400 grams carbohydrate
As for fruitarians, they consume a very low-fat diet, get insufficient protein which I believe raises catabolic hormones and therefore suppresses insulin, and generally waste away on the diet – not gain. Elizabeth also pointed out that fruit has low calorie-density when eaten alone, and is therefore not fattening for that reason.
But it is safe to say that the higher the carb to fat ratio and the starch to sugar ratio, the greater the lean mass gains and thermogenesis when excess calories are consumed.
"Insulin converting carbohydrate into fat? That’s not how insulin works at all. In fact, a solid debunking took place a couple months back athttp://www.carbsanity.blogspot.com/ in which it was shown that the body is in negative fat balance (burning more fat than storing) during postprandial insulin spikes – like the kind you get after having some good old corn starch. On top of that, the easiest carbohydrate to convert to fat has been shown time and time and time and time and time again to be the one that travels to the liver and is digested most slowly. It’s called fructose. Not only does the presence of fat make fat storage easier, if fructose is converted to fat in the liver (which it can be under certain circumstances) it increases insulin resistance, which can lead to increased fat storage (insulin lowers appetite and increases metabolic rate, so becoming unresponsive to the hormone has a tendency to increase appetite and reduce metabolic rate)." Matt Stone
 Fiber also ferments into short-chain fatty acids that have a long list of metabolic benefits, most noticeable being an increase in mitochondrial activity (metabolic rate), insulin sensitivity, and reduced blood levels of cholesterol, triglycerides, and various inflammatory markers.
A low body temperature is known to increase the intensity of the inflammatory response  – perhaps why allergies, food sensitivities, autoimmune disease, and other inflammatory conditions often worsen long-term on various diets of all kinds.
The most weight-set-point-lowering thing you can eat is probably raw, uncooked, unprocessed food.  caffeine and salt can lower weight set point somewhat. Many anecdotally report effortless drops in body weight when cutting out common triggers of allergic or inflammatory reactions, like wheat or dairy products. There are a lot of possibilities here when it comes to changing what you eat or drink that can lower weight set point.
Breakfast eaters typically weigh less, with more muscle mass, than those who skip breakfast.
I think it’s highly variable from person to person, a lot more than food is involved, and age is certainly a factor that works against losing weight spontaneously. Age is a big factor. It seems most people in their teens and twenties go through the refeeding, gaining, and losing process at hyperspeed. Maybe the whole thing will take six months to reach completion at that age for most. The older you get, and the more extremes you’ve been through, the longer it seems to take to actually get to the point of seeing the weight come off, if it ever does. These are just generalizations based on observations.

 http://180degreehealth.com/befriending-insulin/:Insulin, for starters, helps take food energy out of our bloodstream after digestion takes place and packs it away into muscle cells. Wow! I bet that feels really good, stimulates your metabolism, improves your immune system, satisfies your appetite, and makes your muscles grow…. It does.

The problem is, most people’s bodies are NOT working correctly, and the muscle cells are resistant to insulin. This is where the problem lies, and there is no single piece of evidence the world over that suggests, in the slightest degree, that unrefined carbohydrate staples consumed by human beings over the past 10,000 years has anything to do with causing that dysfunction. One of insulin’s wonderful qualities in preventing obesity and metabolic disease is the fact that it is a primary satiating hormone.
Insulin, in the ABSENCE of food, definitely isn’t satiating. It’s deadly. But insulin, under normal circumstances, is an appetite suppressant. Insulin is also the primary driver of muscle growth. Because it packs amino acids and glucose needed for muscle growth into muscle cells, muscle tissue cannot be added very efficiently without insulin present in sizeable quantity.Because of this, among other actions of insulin (such as working in concert with leptin to raise metabolism, suppress appetite, increase lipolysis/fat burning, and so forth), insulin is a profound stimulator of the metabolic rate as well – which is probably why very low-carbohydrate diets, and low-calorie diets, produce huge drops in T3 – the active hormone that regulates metabolism.
Along with the drop in T3 comes drops in testosterone as well – another of the primary hormones involved in building muscle mass and decreasing body fat, which depends upon ample amounts of insulin to be stimulated.
Insulin also works on an axis with the catecholamines – which includes cortisol. When insulin goes up, adrenal activity falls. When insulin goes down, adrenal activity picks up. Keep insulin too low for too long and you run the risk of adrenal fatigue.You are also likely to increase the activity of cortisol (which, unlike carbohydrate ingestion, actually DOES cause insulin resistance) by keeping insulin levels suppressed, which increases insulin resistance, decreases testosterone, decreases fat burning, and otherwise takes you ever-closer to metabolic syndrome.
The result is more body fat and less lean muscle tissue – not to mention a slower metabolism in general, which all ties into the fact that your muscle cells are literally starving. There is no insulin to pump vital matter into cells when insulin is low, and if you return to eating lots of carbohydrates, they are very fattening until the point at which your cortisol levels fall, your metabolism rises, your insulin resistance decreases, and then… finally, your muscle cells start receiving nutrients and you feel better for once.
The ever-popular way to deal with insulin resistance by taking carbohydrates away from a person may have all kinds of benefits in the short-term. This is because chronically-high insulin levels as a result of insulin resistance (not caused by unrefined carbs) are lowered, and many other systems are able to come into balance because of this drop in insulin.
However, it is a dead end, and is not fixing the problem. Eventually, a person on a low-carb diet will run into negative symptoms of insulin deficiency, such as decreased metabolic rate, suppressed fat burning, weight regain, lowered testosterone, decreased immune function, and so forth. This takes a lot longer to take place in an overweight, insulin resistant person, and happens VERY quickly in an insulin sensitive lean person that has no business being on a low-carb diet in the first place.
The best way to bring metabolic syndrome under control? Eat unrefined, nutritious foods to appetite or beyond without severe macronutrient restriction (but an emphasis on starch to increase insulin sensitivity and lower cortisol most quickly), get lots of rest and relaxation, lots of sleep, and whatever else you can do to minimize your burden of stress, inflammation, etc. – ranging from having root canals pulled to treating sleep apnea to decreasing the omega 6 polyunsaturated fat content of your diet. 
Ironically, the hyperinsulinemia epidemic that is sweeping the globe is best solved by befriending insulin and eating plenty of high-quality, nutritious, starchy carbohydrates as well as other foods that stimulate insulin, like beef and cheese. 
For low carbers: I find it can be better to go way to the opposite end of the macronutrient ratio spectrum for a week or two to recover more quickly without the fat gain. Trying to sneak in a few extra carbs slowly after a really long time on a low-carb diet is always a killer though.
Often getting chunky is the exact thing that is required to heal very serious metabolic disorders. In women, a messed up metabolism can increase androgens. In men, you see more of an overproduction of estrogen and low testosterone when metabolism is low.
Insulin is not a stimulator of fat burning when it is present in high amounts. But being able to shuttle nutrients into cells and stimulate the metabolism does increase fat burning in between meals, during sleep, etc. It also allows insulin to fall lower due to increased insulin sensitivity.
I don't need a study to confirm to me that carbohdyrate restriction causes loss of sex drive and reduced sexual function in Matt Stone. I don't need a study to show me that lack of sleep makes me grumpy. I don't need a study to show me that excessive endurance exercise lowers my metabolism… again, these are all facts, not theories.
What I was surprised to hear from Graham, was his thorough understanding of the negatives of eating lots of fat (as well as purine-rich meat) and lots of fruit together – even from wholesome sources. Granted, most of the wholesome sources were omega 6-heavy fat sources like nuts and avocado, which I’ve noticed to be a far worse combo with fruit than primarily saturated fat (like cream or coconut).
Most people try to eat a low-fat diet and cut calories at the same time. This is the worst possible diet known to man. In general, the higher your diet is weighted towards carbohydrates, the greater the muscle mass you will lose while in calorie deficit – and the greatest out-of-control hunger and cravings you will experience.
In fact, calories are more muscle-sparing than protein. The higher in calories you go, the less protein you need to maintain lean body massOther primates average less than 10% of their caloric intake as protein, and generally have a 500% greater ratio of strength to bodyweight than humans. No matter how you examine it, we are an awful lot like other primates.
When you lose weight on a diet, the body’s reaction is to gain weight after. When you gain weight on a non-diet, the body’s reaction is to lose weight after. But I find for some it does take some action – actually obeying your body’s cues for movement and lighter fare instead of perpetually trying to override that with more rest and more food. In other words, you can eat lightly and exercise your brains out and lose weight. If it doesn’t feel like a diet, and your body isn’t shutting down metabolically like you’re on a diet, you’re probably not going to have a post-dieting reaction to it.
One school of thought suggests that certain foods feed “good bacteria.”  I talk about this at length in Diet Recovery, as resistant starches (from starchy foods, beans, whole grains, legumes, chilled starchy foods, Mr. Bean) and foods that don’t fully digest feed “healthy” gut bacteria, resulting in the production of the most metabolically-stimulating of all fatty acids – butyric acid (and other short-chain saturated fatty acids – SCFA’s, thought to generally have a positive health impact). While Peat might acknowledge some benefit here, he seems to believe that there is an even better strategy at addressing this problem – and suggests we eat highly digestible foods that digest completely before they reach the digestive tract, while also eating raw carrots – a food that has an anti-bacterial property that can supposedly help to sterilize the gut (carrots are roots that live in the dark, wet dirt where they must protect themselves from bacterial invasion and have thus developed antibiotic properties).  Linda Bacon discusses this in her excellent book Health at Every Size“Fatter people tend to have a significantly greater proportion of one of the two main types of bacteria found in the gut, known as Firmicutes, than the other, known as Bacteroidetes.  Detailed molecular analyses show that the Firmicutes are much better at extracting calories from food.
When researchers spent a year meticulously measuring the gut flora of the heavier volunteers as they tried to lose weight by eating low-calorie diets, they actually discovered that the proportion of Firmicutes in their digestive tracts rose and the proportion of Bacteroidetes fell. 

Only when my fruit intake eclipses a very large portion of my total diet do the benefits start to take place without the drawbacks (like tooth pain, increased hunger, increased fat, lethargy, anxiety, sleep problems, bleeding gums, zits). If you want to try it, try eating only fruits, 50-50 diluted juices, and starches like rice, potatoes, beans with no added fat or meat until your hunger goes down. It might take a while, but within a week you'll probably start to lose the strong desire to eat something else. At that point you can start slowly working other things into your diet. To me, this is a much better approach than trying to slowly add fruit, which simply doesn't work for those who have this same kind of reaction. 
It’s not the carbohydrate per se that causes the positive insulin-sensitizing impact and enhanced glycemic control.  It’s not necessarily the severe fat restriction either.  It appears that the big drops in triglycerides and increase in insulin sensitivity that commonly occur on the type of diet used by Anderson, as well as in real life in clinical practice by guys like Joel Fuhrman (who prescribes a “beans and greens” approach to reversing type 2 diabetes), result from a heavy intake of fiber – including resistant starch discussed last week, and a high ratio of starch or “complex” carbohydrate to simple sugars. This increases the production of short-chain fatty acids in the gut such as acetate, butyrate, and propionate – discussed in part in this eBook DIET RECOVERY , which increases metabolism, decreases appetite, causes spontaneous weight loss, increases physical activity, drops triglycerides, lowers cholesterol, improves both insulin and leptin sensitivity, and improves HDL to LDL ratio all in one shot.  This also patterns an improvement in gut flora to favor the type of gut flora seen in lean people such as rural Africans as opposed to that seen in the obese, which also provides better resistance to infection and decreased chance of developing bowel cancer, inflammatory bowel disease, and more.
Taube: Fructose is different from any other type of carbohydrate in terms of how it is metabolized.  It passes through the liver where it is known to be converted to fat while increasing the type of cholesterol most associated with heart disease, VLDL – very low-density lipoprotein. Regarding the potential dangers of sugar in the diet, it is important to keep in mind that fructose is converted more efficiently into glycerol phosphate (a molecule associated with the storage of body fat) than is glucose.  This is another reason why fructose stimulates the liver so readily to convert it to triglycerides, and why fructose is considered the most lipogenic carbohydrate.By lipogenic, Taubes means fat-forming.
When you are cold, especially in the hands and feet, your urine is clear, the urge to urinate is strong, or you are peeing frequently… YOU NEED TO EAT MORE AND DRINK LESS. When you are hot, especially in the hands and feet, your urine is dark or you haven’t peed in a really long time… YOU NEED TO EAT LESS AND DRINK MORE.
In my experience a low-carb diet can be very metabolically-suppressive regardless of fluid and salt intake. The glucose seems necessary in order to take advantage of the salt itself, and there are known glucose transporters involved in the process, which is why rehydration drinks always contain glucose.
Too much exercise can interfere with your ability to produce a great deal of body heat at rest. Stress and exhaustion lower the metabolism so you need to sleep enough. When I was working on raising my metabolism, I tried to sleep 10-12 hours per night. Nowadays I only get about 8 hours a night, and my temperature is stable at 98.6.
The most important use of the snack is to lift your body out of an active stress event. It takes a surprisingly miniscule total amount of food to do this. Signs that your body is having a stress event might be cold hands and feet, a sudden urge to urinate, frequent urination, a sudden crash in mood or energy levels, abnormalities in your pulse rate, a headache, nausea, a funky taste in your mouth or dry mouth, a loss of the pink color in your tongue – all kinds of things. Some foods are more “warming” than others. Some of his “superstars” are: cheese, coconut, chocolate, flour, red meat, potatoes, soy sauce, ice cream, and other desserts.

What I was surprised to hear from Graham, was his thorough understanding of the negatives of eating lots of fat (as well as purine-rich meat) and lots of fruit together – even from wholesome sources. Granted, most of the wholesome sources were omega 6-heavy fat sources like nuts and avocado, which I’ve noticed to be a far worse combo with fruit than primarily saturated fat (like cream or coconut), but he understood this “bad combination” quite thoroughly, and had a virtual army of testimonials from people who thought fruit was the enemy, but later found out that the fat was causing their negative fruit experiences.
Even more impressive was Graham’s claim that the biggest cause for failure on his extremely high-carbohydrate, low-fat, low-protein diet was UNDEREATING.

Sluggishness is the new normal, and much of that relates to serotonin and its metabolism-suppressing effect. Reduced metabolism = increased serotonin. Serotonin should be thought as the insulin resistance, hypertension, and hibernation hormone. That's more of its inherent biological function. 

When metabolic rate is low, the tendency to "crash" and have a surge in adrenaline, often referred to by laypersons as "hypoglycemia," is higher. Anxiety levels tend to rise as adrenaline levels rise. But most people don't feel anxiety all the time. It just comes in waves and then goes away. Interestingly, the adrenals often seem to compensate by going into a state of dormancy after adrenaline spikes, and mood and energy levels plummet into more of a depressed state. Mental focus is poor, and energy and motivation are poor. As metabolic rate rises, the tendency to have an adrenaline spike lessens.
Progesterone and thyroid are hormones that trigger greater metabolic activity. This is why, when women ovulate and progesterone rises, body temperature rises typically by a half degree overnight. Powerful stuff.  

Those with hypothyroidism have a hell of a hard time retaining salt. The lower the metabolism, the greater the propensity to develop hyponatremia (low sodium levels). Low-salt diets trigger the stress and inflammation chain reaction in the body – like the kind that leads to hypertension.

The higher the calorie intake, the lower the protein requirements for maintaining muscle mass.  30 grams of protein per day is sufficient for maintaining muscle mass or what is called “nitrogen balance” if you are a normal sized adult male – assuming your calorie intake is quite high.  And it doesn’t take much above that level to trigger muscle growth.
Each pound of new muscle contains about 150 grams of protein.  Hypothetically, a person could still grow a pound of muscle in 10 days with only 15 grams of protein above what is required to maintain nitrogen balance. Thus, eating lots of calories ensures adequate protein for muscle growth.  Protein does stimulate the sympathetic nervous system, and I don’t think doing that in excess is desirable.  Unless you like bone loss and freezing cold hands and toes and hypothyroidism.